Astros Roster & Staff
Transactions
| Date | Transaction |
| 09/12/25 | Houston Astros placed RHP Lance McCullers Jr. on the 15-day injured list. Right hand soreness. |
| 09/12/25 | Houston Astros transferred RHP Luis Garcia from the 15-day injured list to the 60-day injured list. Right elbow discomfort. |
| 09/12/25 | Houston Astros selected the contract of CF Zach Cole from Sugar Land Space Cowboys. |
| 09/12/25 | Houston Astros optioned C César Salazar to Sugar Land Space Cowboys. |
| 09/12/25 | Houston Astros recalled LHP Colton Gordon from Sugar Land Space Cowboys. |
| 09/10/25 | Houston Astros placed RHP Luis Garcia on the 15-day injured list. Right elbow discomfort. |
| 09/10/25 | Houston Astros recalled RHP Nick Hernandez from Sugar Land Space Cowboys. |
| 09/09/25 | Houston Astros recalled RHP J.P. France from Sugar Land Space Cowboys. |
| 09/09/25 | Houston Astros optioned RHP Logan VanWey to Sugar Land Space Cowboys. |
| 09/06/25 | Houston Astros activated CF Jake Meyers from the 10-day injured list. |
| 09/06/25 | Houston Astros optioned LHP Colton Gordon to Sugar Land Space Cowboys. |
| 09/06/25 | Houston Astros recalled RHP Logan VanWey from Sugar Land Space Cowboys. |
| 09/06/25 | Houston Astros optioned LF Jacob Melton to Sugar Land Space Cowboys. |
| 09/05/25 | Houston Astros placed RHP Kaleb Ort on the 15-day injured list. Right elbow inflammation. |
| 09/05/25 | Houston Astros recalled LHP Colton Gordon from Sugar Land Space Cowboys. |
| 09/04/25 | Houston Astros sent RF Pedro León on a rehab assignment to Sugar Land Space Cowboys. |
| 09/03/25 | Houston Astros placed RHP Spencer Arrighetti on the 15-day injured list retroactive to August 31, 2025. Right elbow inflammation. |
| 09/03/25 | Houston Astros activated C Victor Caratini from the 7-day injured list. |
| 09/03/25 | Houston Astros transferred LHP John Rooney from the 15-day injured list to the 60-day injured list. |
| 09/03/25 | Houston Astros optioned LF Chas McCormick to Sugar Land Space Cowboys. |
| 09/03/25 | Houston Astros selected the contract of RHP Jayden Murray from Sugar Land Space Cowboys. |
| 09/03/25 | Los Angeles Angels claimed 1B Logan Davidson off waivers from Houston Astros. |
| 09/01/25 | Houston Astros activated LF Taylor Trammell from the 10-day injured list. |
| 09/01/25 | Houston Astros designated 1B Logan Davidson for assignment. |
| 09/01/25 | Houston Astros activated RHP Luis Garcia from the 60-day injured list. |