White Sox Roster & Staff
Transactions
| Date | Transaction |
| 09/12/25 | Chicago White Sox released RHP Dan Altavilla. |
| 09/10/25 | Chicago White Sox activated 3B Miguel Vargas from the 10-day injured list. |
| 09/10/25 | Chicago White Sox designated RHP Dan Altavilla for assignment. |
| 09/10/25 | Chicago White Sox optioned 3B Bryan Ramos to Charlotte Knights. |
| 09/10/25 | Chicago White Sox recalled RHP Sean Burke from Charlotte Knights. |
| 09/06/25 | Chicago White Sox sent RHP Bryse Wilson outright to Charlotte Knights. |
| 09/05/25 | Chicago White Sox activated RHP Dan Altavilla from the 15-day injured list. |
| 09/05/25 | Chicago White Sox optioned 1B Tim Elko to Charlotte Knights. |
| 09/05/25 | Chicago White Sox selected the contract of RF Dominic Fletcher from Charlotte Knights. |
| 09/05/25 | Chicago White Sox optioned RHP Jonathan Cannon to Charlotte Knights. |
| 09/04/25 | Chicago White Sox placed LHP Bryan Hudson on the 15-day injured list. Lower back strain. |
| 09/04/25 | Chicago White Sox designated RHP Bryse Wilson for assignment. |
| 09/04/25 | Chicago White Sox recalled LHP Tyler Gilbert from Charlotte Knights. |
| 09/04/25 | Chicago White Sox recalled RHP Jonathan Cannon from Charlotte Knights. |
| 09/03/25 | Chicago White Sox optioned 3B Ben Cowles to Charlotte Knights. |
| 09/03/25 | Chicago White Sox claimed 3B Ben Cowles off waivers from Chicago Cubs. |
| 09/02/25 | Chicago White Sox recalled LHP Bryan Hudson from Charlotte Knights. |
| 09/02/25 | Chicago White Sox optioned LHP Cam Booser to Charlotte Knights. |
| 09/01/25 | Chicago White Sox recalled LHP Fraser Ellard from Charlotte Knights. |
| 09/01/25 | Chicago White Sox recalled 3B Bryan Ramos from Charlotte Knights. |