Guardians Roster & Staff
Transactions
| Date | Transaction |
| 09/04/25 | Cleveland Guardians placed RHP Nic Enright on the 15-day injured list. Right elbow/forearm inflammation. |
| 09/04/25 | Cleveland Guardians recalled RHP Zak Kent from Columbus Clippers. |
| 09/03/25 | Cleveland Guardians recalled LHP Joey Cantillo from Columbus Clippers. |
| 09/03/25 | Cleveland Guardians optioned RHP Zak Kent to Columbus Clippers. |
| 09/02/25 | Cleveland Guardians sent CF Lane Thomas on a rehab assignment to Akron RubberDucks. |
| 09/01/25 | Cleveland Guardians optioned 3B Will Wilson to Columbus Clippers. |
| 09/01/25 | Cleveland Guardians recalled RF Jhonkensy Noel from Columbus Clippers. |
| 09/01/25 | Cleveland Guardians selected the contract of RF George Valera from Columbus Clippers. |
| 09/01/25 | Cleveland Guardians recalled RHP Zak Kent from Columbus Clippers. |