Cardinals Roster & Staff
Transactions
| Date | Transaction |
| 04/30/25 | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| 04/28/25 | St. Louis Cardinals designated RHP Ryan Loutos for assignment. |
| 04/28/25 | St. Louis Cardinals selected the contract of SS Jose Barrero from Memphis Redbirds. |
| 04/28/25 | St. Louis Cardinals optioned SS Thomas Saggese to Memphis Redbirds. |
| 04/25/25 | St. Louis Cardinals optioned RHP Ryan Fernandez to Memphis Redbirds. |
| 04/25/25 | St. Louis Cardinals recalled RHP Riley O'Brien from Memphis Redbirds. |
| 04/22/25 | St. Louis Cardinals activated SS Masyn Winn from the 10-day injured list. |
| 04/22/25 | St. Louis Cardinals optioned CF Michael Siani to Memphis Redbirds. |
| 04/18/25 | St. Louis Cardinals sent SS Masyn Winn on a rehab assignment to Memphis Redbirds. |
| 04/18/25 | St. Louis Cardinals signed free agent RHP Conor Steinbaugh to a minor league contract. |
| 04/16/25 | RHP Andre Pallante changed number to 53. |
| 04/16/25 | LHP Matthew Liberatore changed number to 52. |
| 04/16/25 | LHP Steven Matz changed number to 32. |
| 04/16/25 | St. Louis Cardinals signed free agent C Andy Yerzy to a minor league contract. |
| 04/16/25 | RF Lars Nootbaar changed number to 21. |
| 04/16/25 | RHP Ryan Helsley changed number to 56. |
| 04/16/25 | RHP Miles Mikolas changed number to 39. |
| 04/16/25 | IF Brendan Donovan changed number to 33. |
| 04/16/25 | 1B Luken Baker changed number to 26. |
| 04/16/25 | 3B Nolan Arenado changed number to 28. |
| 04/16/25 | RHP Phil Maton changed number to 88. |
| 04/16/25 | RHP Erick Fedde changed number to 12. |
| 04/16/25 | 2B Thomas Saggese changed number to 25. |
| 04/16/25 | C Yohel Pozo changed number to 63. |
| 04/16/25 | CF Victor Scott II changed number to 11. |
| 04/16/25 | RHP Kyle Leahy changed number to 62. |
| 04/16/25 | RHP Roddery Muñoz changed number to 35. |
| 04/16/25 | C Pedro Pagés changed number to 43. |
| 04/16/25 | RF Jordan Walker changed number to 18. |
| 04/16/25 | LHP John King changed number to 47. |
| 04/16/25 | CF Michael Siani changed number to 22. |
| 04/16/25 | RHP Ryan Fernandez changed number to 64. |
| 04/16/25 | 1B Alec Burleson changed number to 41. |
| 04/16/25 | RHP Sonny Gray changed number to 54. |
| 04/16/25 | LHP JoJo Romero changed number to 59. |
| 04/16/25 | 1B Willson Contreras changed number to 40. |
| 04/16/25 | 2B Nolan Gorman changed number to 16. |
| 04/16/25 | St. Louis Cardinals recalled RHP Matt Svanson from Memphis Redbirds. |
| 04/16/25 | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| 04/15/25 | RHP Andre Pallante changed number to 42. |
| 04/15/25 | RHP Ryan Helsley changed number to 42. |
| 04/15/25 | RF Lars Nootbaar changed number to 42. |
| 04/15/25 | IF Brendan Donovan changed number to 42. |
| 04/15/25 | 3B Nolan Arenado changed number to 42. |
| 04/15/25 | 1B Willson Contreras changed number to 42. |
| 04/15/25 | St. Louis Cardinals signed free agent RHP Ricardo Velez to a minor league contract. |
| 04/15/25 | CF Michael Siani changed number to 42. |
| 04/15/25 | RF Jordan Walker changed number to 42. |
| 04/15/25 | RHP Sonny Gray changed number to 42. |
| 04/15/25 | LHP John King changed number to 42. |
| 04/15/25 | 1B Alec Burleson changed number to 42. |
| 04/15/25 | LHP Matthew Liberatore changed number to 42. |
| 04/15/25 | 2B Nolan Gorman changed number to 42. |
| 04/15/25 | LHP Steven Matz changed number to 42. |
| 04/15/25 | RHP Miles Mikolas changed number to 42. |
| 04/15/25 | RHP Phil Maton changed number to 42. |
| 04/15/25 | CF Victor Scott II changed number to 42. |
| 04/15/25 | RHP Erick Fedde changed number to 42. |
| 04/15/25 | 2B Thomas Saggese changed number to 42. |
| 04/15/25 | RHP Roddery Muñoz changed number to 42. |
| 04/15/25 | 1B Luken Baker changed number to 42. |
| 04/15/25 | RHP Ryan Fernandez changed number to 42. |
| 04/15/25 | C Pedro Pagés changed number to 42. |
| 04/15/25 | C Yohel Pozo changed number to 42. |
| 04/15/25 | RHP Kyle Leahy changed number to 42. |
| 04/15/25 | LHP JoJo Romero changed number to 42. |
| 04/12/25 | St. Louis Cardinals activated 2B Nolan Gorman from the 10-day injured list. |
| 04/12/25 | St. Louis Cardinals placed SS Masyn Winn on the 10-day injured list. Lower back spasms. |
| 04/11/25 | St. Louis Cardinals recalled RHP Roddery Muñoz from Memphis Redbirds. |
| 04/10/25 | St. Louis Cardinals optioned RHP Chris Roycroft to Memphis Redbirds. |
| 04/07/25 | St. Louis Cardinals placed C Iván Herrera on the 10-day injured list. Left knee inflammation. |
| 04/07/25 | St. Louis Cardinals transferred LHP Zack Thompson from the 15-day injured list to the 60-day injured list. Left shoulder strain. |
| 04/07/25 | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| 04/07/25 | St. Louis Cardinals selected the contract of C Yohel Pozo from Memphis Redbirds. |
| 04/06/25 | St. Louis Cardinals recalled RHP Gordon Graceffo from Memphis Redbirds. |
| 04/04/25 | St. Louis Cardinals placed 2B Nolan Gorman on the 10-day injured list retroactive to April 2, 2025. Right hamstring strain. |
| 04/04/25 | St. Louis Cardinals recalled 2B Thomas Saggese from Memphis Redbirds. |