Padres Roster & Staff
Transactions
| Date | Transaction |
| 07/31/25 | Athletics traded RHP Mason Miller and LHP JP Sears to San Diego Padres for RHP Henry Baez, RHP Eduarniel Núñez, SS Leo De Vries and RHP Braden Nett. |
| 07/31/25 | Athletics traded RHP Mason Miller and LHP JP Sears to San Diego Padres for RHP Henry Baez, RHP Eduarniel Núñez, SS Leo De Vries and RHP Braden Nett. |
| 07/31/25 | Athletics traded RHP Mason Miller and LHP JP Sears to San Diego Padres for RHP Henry Baez, RHP Eduarniel Núñez, SS Leo De Vries and RHP Braden Nett. |
| 07/31/25 | Athletics traded RHP Mason Miller and LHP JP Sears to San Diego Padres for RHP Henry Baez, RHP Eduarniel Núñez, SS Leo De Vries and RHP Braden Nett. |
| 07/31/25 | Athletics traded RHP Mason Miller and LHP JP Sears to San Diego Padres for RHP Henry Baez, RHP Eduarniel Núñez, SS Leo De Vries and RHP Braden Nett. |
| 07/31/25 | Athletics traded RHP Mason Miller and LHP JP Sears to San Diego Padres for RHP Henry Baez, RHP Eduarniel Núñez, SS Leo De Vries and RHP Braden Nett. |
| 07/31/25 | Kansas City Royals traded C Freddy Fermin to San Diego Padres for RHP Ryan Bergert and RHP Stephen Kolek. |
| 07/31/25 | Kansas City Royals traded C Freddy Fermin to San Diego Padres for RHP Ryan Bergert and RHP Stephen Kolek. |
| 07/31/25 | Kansas City Royals traded C Freddy Fermin to San Diego Padres for RHP Ryan Bergert and RHP Stephen Kolek. |
| 07/29/25 | San Diego Padres recalled RHP Ryan Bergert from El Paso Chihuahuas. |
| 07/29/25 | San Diego Padres optioned RHP Stephen Kolek to El Paso Chihuahuas. |
| 07/25/25 | San Diego Padres recalled RHP Ron Marinaccio from El Paso Chihuahuas. |
| 07/25/25 | San Diego Padres optioned LHP Kyle Hart to El Paso Chihuahuas. |
| 07/24/25 | San Diego Padres signed free agent OF Qrey Lott to a minor league contract. |
| 07/24/25 | San Diego Padres signed free agent C Jake Bold to a minor league contract. |
| 07/24/25 | San Diego Padres signed free agent SS Bradley Frye to a minor league contract. |
| 07/24/25 | San Diego Padres signed free agent RHP Brandon Langley to a minor league contract. |
| 07/24/25 | San Diego Padres signed SS Dylan Grego. |
| 07/24/25 | San Diego Padres signed free agent LHP Cal Riehl to a minor league contract. |
| 07/24/25 | San Diego Padres signed LHP Kruz Schoolcraft. |
| 07/24/25 | San Diego Padres signed free agent RHP Cameron Nohos to a minor league contract. |
| 07/24/25 | San Diego Padres signed RHP Michael Salina. |
| 07/24/25 | San Diego Padres signed RHP Tyler Schmitt. |
| 07/24/25 | San Diego Padres signed RHP Clay Edmondson. |
| 07/24/25 | San Diego Padres signed LHP Ryan Reed. |
| 07/24/25 | San Diego Padres signed OF Cardell Thibodeaux. |
| 07/24/25 | San Diego Padres signed free agent OF Conner Westenburg to a minor league contract. |
| 07/24/25 | San Diego Padres signed free agent RHP Charlie Walker to a minor league contract. |
| 07/24/25 | San Diego Padres signed C Truitt Madonna. |
| 07/24/25 | San Diego Padres signed free agent SS Dawson Willis to a minor league contract. |
| 07/24/25 | San Diego Padres signed C Ty Harvey. |
| 07/24/25 | San Diego Padres signed SS Jonathan Vastine. |
| 07/24/25 | San Diego Padres signed free agent RHP Tyler Dietz to a minor league contract. |
| 07/24/25 | San Diego Padres signed OF George Bilecki. |
| 07/24/25 | San Diego Padres signed 1B Luke Cantwell. |
| 07/24/25 | San Diego Padres signed RHP Landry Jurecka. |
| 07/24/25 | San Diego Padres signed free agent RHP Nick Falter to a minor league contract. |
| 07/24/25 | San Diego Padres signed OF Ryan Wideman. |
| 07/23/25 | San Diego Padres signed SS Justin DeCriscio. |
| 07/23/25 | San Diego Padres signed RHP Jaxon Dalena. |
| 07/23/25 | San Diego Padres signed LHP Jamie Hitt. |
| 07/23/25 | San Diego Padres signed RHP Will Koger. |
| 07/23/25 | San Diego Padres signed 3B Kerrington Cross. |
| 07/22/25 | San Diego Padres recalled LHP Kyle Hart from El Paso Chihuahuas. |
| 07/22/25 | San Diego Padres recalled RHP Stephen Kolek from El Paso Chihuahuas. |
| 07/22/25 | San Diego Padres optioned RHP Bryan Hoeing to El Paso Chihuahuas. |
| 07/22/25 | San Diego Padres optioned RHP Alek Jacob to El Paso Chihuahuas. |
| 07/21/25 | San Diego Padres signed free agent LHP Enmanuel Polo to a minor league contract. |
| 07/16/25 | San Diego Padres activated LF Gavin Sheets from the paternity list. |
| 07/16/25 | San Diego Padres signed RHP Misael Tamarez. |
| 07/15/25 | San Diego Padres optioned C Luis Campusano to El Paso Chihuahuas. |
| 07/13/25 | San Diego Padres placed LF Gavin Sheets on the paternity list. |
| 07/13/25 | San Diego Padres signed free agent C Joseph Uzeta to a minor league contract. |
| 07/13/25 | San Diego Padres recalled C Luis Campusano from El Paso Chihuahuas. |
| 07/12/25 | San Diego Padres recalled RHP Alek Jacob from El Paso Chihuahuas. |
| 07/12/25 | San Diego Padres optioned RHP Ryan Bergert to El Paso Chihuahuas. |
| 07/11/25 | San Diego Padres activated RHP Ryan Bergert from the 15-day injured list. |
| 07/11/25 | San Diego Padres optioned RHP Eduarniel Núñez to El Paso Chihuahuas. |
| 07/07/25 | San Diego Padres transferred RHP Michael King from the 15-day injured list to the 60-day injured list. Right shoulder inflammation. |
| 07/07/25 | San Diego Padres activated RHP Yu Darvish from the 60-day injured list. |
| 07/07/25 | San Diego Padres optioned LHP Kyle Hart to El Paso Chihuahuas. |
| 07/06/25 | San Diego Padres sent RHP Ryan Bergert on a rehab assignment to El Paso Chihuahuas. |
| 07/06/25 | San Diego Padres optioned RHP Stephen Kolek to El Paso Chihuahuas. |
| 07/06/25 | San Diego Padres recalled LHP Kyle Hart from El Paso Chihuahuas. |
| 07/03/25 | San Diego Padres optioned RHP Ron Marinaccio to El Paso Chihuahuas. |
| 07/02/25 | San Diego Padres recalled RHP Ron Marinaccio from El Paso Chihuahuas. |
| 07/02/25 | San Diego Padres sent RHP Logan Gillaspie outright to El Paso Chihuahuas. |
| 07/02/25 | San Diego Padres optioned RHP Matt Waldron to El Paso Chihuahuas. |
| 07/02/25 | San Diego Padres selected the contract of RHP Eduarniel Núñez from El Paso Chihuahuas. |